Tesamorelin 20mg

Benefits:

• Elevates natural growth hormone release by approximately 60%

• Doubles natural IGF-1 output

• Promotes reduction of visceral fat

• Supports healthy cholesterol levels

• Does not alter ghrelin secretion

• No increase in appetite

• Does not raise cortisol or prolactin, unlike other secretagogues

Tesamorelin is a synthetic analogue of growth hormone-releasing hormone (GHRH) that stimulates growth hormone secretion via direct activation of the pituitary gland’s GHRH receptors. This targeted mechanism sets it apart from agents like MK-677, as Tesamorelin does not interact with the ghrelin receptor (GHSR-1a) and avoids elevating ghrelin levels. This distinction enhances its versatility: Tesamorelin can be utilized during either muscle-building or cutting phases, and its ability to preferentially target visceral fat stems from its clinical use in lipodystrophy.

Pharmacokinetic studies indicate Tesamorelin triggers a rapid, acute spike in growth hormone immediately post-administration, though this effect diminishes after about one hour. In contrast, IGF-1 remains stably elevated for over 20 hours, ensuring prolonged anabolic and metabolic benefits.